Ionis Pharmaceuticals, Inc. Stock Performance
as on September 16, 2025 at 11:40 pm IST
Day's Low
Day's High
$60.69$61.54
0.34%
Downside
1.05%
Upside
52 Week's Low
52 Week's High
$23.95$64.7260.67%
Downside
6.26%
Upside
Ionis Pharmaceuticals, Inc. share price movements today
- Previous Close
- $61.10
- Open
- $61.01
- Volume
- 665.8K
- Day's Low - High
- $60.69 - $61.54
- 52 Week Low - High
- $23.95 - $64.72
Ionis Pharmaceuticals, Inc. Historical Returns
- 1 Month Return
- + 39.56 %
- 3 Month Return
- + 73.38 %
- 1 Year Return
- + 50.12 %
- 3 Year Return
- + 31.88 %
- 5 Year Return
- + 18.02 %
Ionis Pharmaceuticals, Inc. Stock Fundamentals & Key Indicators
Check Ionis Pharmaceuticals, Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$10.1B
EPS (TTM)
-1.8916
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
-0.44%
PE Ratio (TTM)
-19.95
Industry PE ratio
10.127857142857144
P/B Ratio
0PEG Ratio
25.7033
EBITDA
-255.2M
Revenue (TTM)
944.0M
Profit Margin
-28.41%
Return On Equity TTM
3092300.00%
Ionis Pharmaceuticals, Inc. Stock Valuation
Track how Ionis Pharmaceuticals, Inc. P/E has moved over time to understand its valuation trends.
Ionis Pharmaceuticals, Inc. in the last 5 years
Lowest (91.06x)
September 30, 2020
Today (-19.95x)
September 16, 2025
Industry (10.13x)
September 16, 2025
Highest (91.06x)
September 30, 2020
Today’s Price to Earnings Ratio: -19.95x
Ionis Pharmaceuticals, Inc. vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Ionis Pharmaceuticals, Inc. with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $10.1B | 18.02% | -19.95 | -28.41% | |
| BUY | $61.1B | 251.26% | -505.15 | -12.96% | |
| NA | $38.7B | NA | NA | -3.89% | |
| BUY | $101.2B | 47.46% | 28.09 | 31.86% | |
| BUY | $59.6B | 0.6% | 14.1 | 31.37% |
Stock Returns calculator for Ionis Pharmaceuticals, Inc. Stock including INR - Dollar returns
The Ionis Pharmaceuticals, Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Ionis Pharmaceuticals, Inc. investment value today
Current value as on today
₹1,54,499
Returns
₹54,499
(+54.5%)
Returns from Ionis Pharmaceuticals, Inc. Stock
₹49,631 (+49.63%)
Dollar Returns*
₹4,867 (+4.87%)
Analyst Recommendation on Ionis Pharmaceuticals, Inc. Stock
Based on 30 analysts
66.67%
Buy
23.33%
Hold
10.00%
Sell
Based on 30 analysts, 66.67% of analysts recommend a 'BUY' rating for Ionis Pharmaceuticals, Inc.. Average target price of $68.88
Ionis Pharmaceuticals, Inc. Share Price Target
Get share price movements and forecasts by analysts on Ionis Pharmaceuticals, Inc..
What analysts predicted
11.59%UPSIDE
Target Price
$68.88
Current Price
$60.9
Analyzed by
30 Analysts
Target
$68.88
Ionis Pharmaceuticals, Inc. target price $68.88, a slight upside of 11.59% compared to current price of $60.9. According to 30 analysts rating.
Ionis Pharmaceuticals, Inc. Stock's Interest Amongst Investors
Search interest for Ionis Pharmaceuticals, Inc. Stock has increased by 196% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:196% versus previous 30 day period
Ionis Pharmaceuticals, Inc. Quarterly Profit & Loss
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Annual Profit & Loss
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Quarterly Cash Flow
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Annual Cash Flow
All numbers in Millions USD
Global Institutional Holdings in Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. News & Key Events
Today's Timeline - 09 September
Tue, 11:21 PM
-FDA grants Breakthrough Therapy designation to Ionis Pharmaceuticals' ION582 for Angelman syndrome, following promising clinical trial results.
Insights on Ionis Pharmaceuticals, Inc.
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise
In the last 1 month, IONS stock has moved up by 39.6%
- POSITIVE IMPACT
Revenue Rich
Revenue is up for the last 2 quarters, 131.61M → 452.04M (in $), with an average increase of 70.9% per quarter
- POSITIVE IMPACT
Profit Spike
Netprofit is up for the last 2 quarters, -146.93M → 123.55M (in $), with an average increase of 218.9% per quarter
NO EFFECTAgainst Peers
In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 116.5% return, outperforming this stock by 84.6%
- NO EFFECT
Against Peers
In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 70.6% return, outperforming this stock by 20.5%
About Ionis Pharmaceuticals, Inc.
| Organisation | Ionis Pharmaceuticals, Inc. |
| Headquarters | 2855 Gazelle Court, Carlsbad, CA, United States, 92010 |
| Industry | Health Technology |
| CEO | Dr. Brett P. Monia Ph.D. |
| E-voting on shares | Click here to vote |
Key Management of Ionis Pharmaceuticals, Inc.
Name | Title |
|---|---|
Mr. D. Wade Walke Ph.D. | Senior Vice President of Investor Relations |
Ms. Tracy Berns J.D. | Senior VP and Chief Compliance & Quality Assurance Officer |
Ms. Elizabeth L. Hougen M.A., M.B.A., M.S. | Executive VP of Finance & CFO |
Dr. Richard S. Geary Ph.D. | Executive VP & Chief Development Officer |
Mr. Kyle Jenne | Executive VP & Chief Global Product Strategy Officer |
Dr. C. Frank Bennett BSc, Ph.D. | Executive VP & Chief Scientific Officer |
Dr. Brett P. Monia Ph.D. | Founder, CEO & Director |
Mr. Patrick R. O'Neil Esq. | Executive VP, Chief Legal Officer, General Counsel & Corporate Secretary |
Mr. Darren Gonzales | Chief Accounting Officer & Senior VP |
Ms. Hayley Soffer | Vice President of Corporate Communications |
FAQs
What is Ionis Pharmaceuticals, Inc. share price today?
Ionis Pharmaceuticals, Inc. share price today is $60.9 as on . Ionis Pharmaceuticals, Inc. share today touched a day high of $61.54 and a low of $60.69.
What is the 52 week high and 52 week low for Ionis Pharmaceuticals, Inc. share?
Ionis Pharmaceuticals, Inc. share touched a 52 week high of $64.72 on and a 52 week low of $23.95 on . Ionis Pharmaceuticals, Inc. stock price today i.e. is trending at $60.9,which is 5.90% down from its 52 week high and 154.28% up from its 52 week low.
What is Ionis Pharmaceuticals, Inc.'s market capitalisation today?
Ionis Pharmaceuticals, Inc. market capitalisation is $0.01T as on .
How to invest in Ionis Pharmaceuticals, Inc. Stock (IONS) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Ionis Pharmaceuticals, Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Ionis Pharmaceuticals, Inc. Shares that will get you 0.0246 shares as per Ionis Pharmaceuticals, Inc. share price of $60.9 per share as on September 16, 2025 at 11:40 pm IST.
What is the minimum amount required to buy Ionis Pharmaceuticals, Inc. Stock (IONS) from India?
Indian investors can start investing in Ionis Pharmaceuticals, Inc. (IONS) shares with as little as ₹88.042 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹880.42 in Ionis Pharmaceuticals, Inc. stock (as per the Rupee-Dollar exchange rate as on ).
Based on Ionis Pharmaceuticals, Inc. share’s latest price of $60.9 as on September 16, 2025 at 11:40 pm IST, you will get 0.1642 shares of Ionis Pharmaceuticals, Inc.. Learn more about
fractional shares .
What are the returns that Ionis Pharmaceuticals, Inc. has given to Indian investors in the last 5 years?
Ionis Pharmaceuticals, Inc. stock has given 18.02% share price returns and 20.01% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?