Ionis Pharmaceuticals, Inc. Stock Performance
as on March 21, 2026 at 6:59 am IST
Day's Low
Day's High
$70.52$72.59
0.76%
Downside
2.15%
Upside

52 Week's Low
52 Week's High
$23.95$86.74
66.30%
Downside
22.07%
Upside

Ionis Pharmaceuticals, Inc. share price movements today
- Previous Close
- $71.32
- Open
- $71.96
- Volume
- 1.3M
- Day's Low - High
- $70.52 - $72.59
- 52 Week Low - High
- $23.95 - $86.74
Ionis Pharmaceuticals, Inc. Historical Returns
- 1 Month Return
- -16.09 %
- 3 Month Return
- -11.63 %
- 1 Year Return
- + 115.71 %
- 3 Year Return
- + 111.15 %
- 5 Year Return
- + 62.86 %
Ionis Pharmaceuticals, Inc. Stock Fundamentals & Key Indicators
Check Ionis Pharmaceuticals, Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$11.7B
EPS (TTM)
-3.2429
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
-0.44%
PE Ratio (TTM)
-19.95
Industry PE ratio
7.887522123893805
PEG Ratio
25.7033
EBITDA
-369.2M
Revenue (TTM)
943.7M
Profit Margin
-40.41%
Return On Equity TTM
-70.80%
Ionis Pharmaceuticals, Inc. Stock Valuation
Track how Ionis Pharmaceuticals, Inc. P/E has moved over time to understand its valuation trends.
Ionis Pharmaceuticals, Inc. in the last 5 years
Lowest (-163.66x)
March 31, 2022
Today (-19.95x)
March 23, 2026
Industry (7.89x)
March 23, 2026
Highest (-10.69x)
September 30, 2023
Today’s Price to Earnings Ratio: -19.95x
Ionis Pharmaceuticals, Inc. vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Ionis Pharmaceuticals, Inc. with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $11.7B | 62.86% | -19.95 | -40.41% | |
| BUY | $41.4B | 125.13% | 133.41 | 8.45% | |
| BUY | $115.3B | 112.56% | 29.67 | 32.94% | |
| NA | $31.6B | NA | 111 | 5.37% | |
| BUY | $77.5B | 56.01% | 17.67 | 31.41% |
Stock Returns calculator for Ionis Pharmaceuticals, Inc. Stock including INR - Dollar returns
The Ionis Pharmaceuticals, Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Ionis Pharmaceuticals, Inc. investment value today
Current value as on today
₹2,25,367
Returns
₹1,25,367
(+125.37%)
Returns from Ionis Pharmaceuticals, Inc. Stock
₹1,15,922 (+115.92%)
Dollar Returns*
₹9,445 (+9.44%)
Analyst Recommendation on Ionis Pharmaceuticals, Inc. Stock
Based on 30 analysts
66.67%
Buy
23.33%
Hold
10.00%
Sell
Based on 30 analysts, 66.67% of analysts recommend a 'BUY' rating for Ionis Pharmaceuticals, Inc.. Average target price of $93.9
Ionis Pharmaceuticals, Inc. Share Price Target
Get share price movements and forecasts by analysts on Ionis Pharmaceuticals, Inc..
What analysts predicted
24.32%UPSIDE
Target Price
$93.9
Current Price
$71.06
Analyzed by
30 Analysts
Target
$93.90
Ionis Pharmaceuticals, Inc. target price $93.9, a slight upside of 24.32% compared to current price of $71.06. According to 30 analysts rating.
Ionis Pharmaceuticals, Inc. Stock’s Investor Sentiment and Interest
Search interest for Ionis Pharmaceuticals, Inc. Stock has decreased by -63% in the last 30 days, reflecting a downward trend in search activity.
Time period: to
Ionis Pharmaceuticals, Inc. Quarterly Profit & Loss
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Annual Profit & Loss
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Quarterly Cash Flow
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. Annual Cash Flow
All numbers in Millions USD
Ionis Pharmaceuticals, Inc. News & Key Events

Today's Timeline - 08 October
Wed, 05:57 PM
-JPMorgan upgrades Ionis Pharmaceuticals to overweight, raising price target to $80, citing strong drug pipeline and potential for breakeven.
Insights on Ionis Pharmaceuticals, Inc.
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise

In the last 1 year, IONS stock has moved up by 115.7%
POSITIVE IMPACTBest in 1 Year

In the last 1 year, IONS has outperformed top 5 stocks with highest market-cap in its industry
POSITIVE IMPACTRevenue Rich

Revenue is up for the last 2 quarters, 156.71M → 203.0M (in $), with an average increase of 22.8% per quarter
POSITIVE IMPACTBest in 3 Years

In the last 3 years, IONS has outperformed top 5 stocks with highest market-cap in its industry
NEGATIVE IMPACTProfit Down

Netprofit is down for the last 3 quarters, 123.55M → -229.0M (in $), with an average decrease of 141.1% per quarter
About Ionis Pharmaceuticals, Inc.
| Organisation | Ionis Pharmaceuticals, Inc. |
| Headquarters | 2855 Gazelle Court, Carlsbad, CA, United States, 92010 |
| Industry | Health Technology |
| CEO | Dr. Brett P. Monia Ph.D. |
| E-voting on shares | Click here to vote |
Key Management of Ionis Pharmaceuticals, Inc.
Name | Title |
|---|---|
Dr. C. Frank Bennett BSc, Ph.D. | Executive VP & Chief Scientific Officer |
Mr. Patrick R. O'Neil Esq. | Executive VP, Chief Legal Officer, General Counsel & Corporate Secretary |
Mr. Kyle Jenne | Executive VP & Chief Global Product Strategy Officer |
Dr. Eugene Schneider M.D. | Executive VP, Chief Clinical Development & Operations Officer |
Mr. Darren Gonzales | Chief Accounting Officer & Senior VP |
Mr. D. Wade Walke Ph.D. | Senior Vice President of Investor Relations |
Ms. Tracy Berns J.D. | Senior VP and Chief Compliance & Quality Assurance Officer |
Dr. Brett P. Monia Ph.D. | Founder, CEO & Director |
Ms. Elizabeth L. Hougen M.A., M.B.A., M.S. | Executive VP of Finance & CFO |
Dr. Richard S. Geary Ph.D. | Strategic Consultant |
FAQs
What is Ionis Pharmaceuticals, Inc. share price today?
Ionis Pharmaceuticals, Inc. share price today is $71.06 as on at the close of the market. Ionis Pharmaceuticals, Inc. share today touched a day high of $72.59 and a low of $70.52.
What is the 52 week high and 52 week low for Ionis Pharmaceuticals, Inc. share?
Ionis Pharmaceuticals, Inc. share touched a 52 week high of $86.74 on and a 52 week low of $23.95 on . Ionis Pharmaceuticals, Inc. stock price today i.e. is closed at $71.06,which is 18.08% down from its 52 week high and 196.70% up from its 52 week low.
What is Ionis Pharmaceuticals, Inc.'s market capitalisation today?
Ionis Pharmaceuticals, Inc. market capitalisation is $0.01T as on .
How to invest in Ionis Pharmaceuticals, Inc. Stock (IONS) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Ionis Pharmaceuticals, Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Ionis Pharmaceuticals, Inc. Shares that will get you 0.0211 shares as per Ionis Pharmaceuticals, Inc. share price of $71.06 per share as on March 21, 2026 at 1:29 am IST.
What is the minimum amount required to buy Ionis Pharmaceuticals, Inc. Stock (IONS) from India?
Indian investors can start investing in Ionis Pharmaceuticals, Inc. (IONS) shares with as little as ₹93.652 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹936.52 in Ionis Pharmaceuticals, Inc. stock (as per the Rupee-Dollar exchange rate as on ).
Based on Ionis Pharmaceuticals, Inc. share’s latest price of $71.06 as on March 21, 2026 at 1:29 am IST, you will get 0.1407 shares of Ionis Pharmaceuticals, Inc.. Learn more about
fractional shares .
What are the returns that Ionis Pharmaceuticals, Inc. has given to Indian investors in the last 5 years?
Ionis Pharmaceuticals, Inc. stock has given 62.86% share price returns and 28.37% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?