Karyopharm Therapeutics Inc Stock Performance
as on October 18, 2025 at 1:29 am IST
Day's Low
Day's High
$5.76$6
3.84%
Downside
0.17%
Upside
52 Week's Low
52 Week's High
$3.51$16.9541.40%
Downside
182.97%
Upside
Karyopharm Therapeutics Inc share price movements today
- Previous Close
- $6.03
- Open
- $5.96
- Volume
- 214.4K
- Day's Low - High
- $5.76 - $6
- 52 Week Low - High
- $3.51 - $16.95
Karyopharm Therapeutics Inc Historical Returns
- 1 Month Return
- + 3.49 %
- 3 Month Return
- + 54.03 %
- 1 Year Return
- -54.56 %
- 3 Year Return
- -91.92 %
- 5 Year Return
- -97.5 %
Karyopharm Therapeutics Inc Stock Fundamentals & Key Indicators
Check Karyopharm Therapeutics Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$94.4M
EPS (TTM)
-10.515
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.00%
PE Ratio (TTM)
-1.07
Industry PE ratio
-0.32286624203821657
PEG Ratio
-0.15
EBITDA
-114.9M
Revenue (TTM)
137.3M
Profit Margin
-90.02%
Return On Equity TTM
0.00%
Karyopharm Therapeutics Inc Stock Valuation
Track how Karyopharm Therapeutics Inc P/E has moved over time to understand its valuation trends.
Karyopharm Therapeutics Inc in the last 5 years
Lowest (-84.88x)
December 31, 2020
Today (-1.07x)
October 18, 2025
Industry (-0.32x)
October 18, 2025
Highest (-0.34x)
June 30, 2025
Today’s Price to Earnings Ratio: -1.07x
Karyopharm Therapeutics Inc vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Karyopharm Therapeutics Inc with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $94.4M | -97.5% | -1.07 | -90.02% | |
| BUY | $63.1B | 231.27% | -505.15 | -12.96% | |
| NA | $36.7B | NA | NA | -3.89% | |
| BUY | $104.8B | 91.13% | 29.04 | 31.86% | |
| BUY | $60.3B | -3.62% | 14.35 | 31.37% |
Stock Returns calculator for Karyopharm Therapeutics Inc Stock including INR - Dollar returns
The Karyopharm Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Karyopharm Therapeutics Inc investment value today
Current value as on today
₹50,695
Returns
Returns from Karyopharm Therapeutics Inc Stock
Dollar Returns*
₹4,794 (+4.79%)
Analyst Recommendation on Karyopharm Therapeutics Inc Stock
Based on 13 analysts
84.62%
Buy
15.38%
Hold
0.00%
Sell
Based on 13 analysts, 84.62% of analysts recommend a 'BUY' rating for Karyopharm Therapeutics Inc. Average target price of $15.67
Karyopharm Therapeutics Inc Share Price Target
Get share price movements and forecasts by analysts on Karyopharm Therapeutics Inc.
What analysts predicted
61.77%UPSIDE
Target Price
$15.67
Current Price
$5.99
Analyzed by
13 Analysts
Target
$15.67
Karyopharm Therapeutics Inc target price $15.67, a slight upside of 61.77% compared to current price of $5.99. According to 13 analysts rating.
Karyopharm Therapeutics Inc Stock’s Investor Sentiment and Interest
Search interest for Karyopharm Therapeutics Inc Stock has increased by 69% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:69% versus previous 30 day period
Karyopharm Therapeutics Inc Quarterly Profit & Loss
All numbers in Millions USD
Karyopharm Therapeutics Inc Annual Profit & Loss
All numbers in Millions USD
Karyopharm Therapeutics Inc Quarterly Cash Flow
All numbers in Millions USD
Karyopharm Therapeutics Inc Annual Cash Flow
All numbers in Millions USD
Karyopharm Therapeutics Inc News & Key Events
Insights on Karyopharm Therapeutics Inc
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise
In the last 7 days, KPTI stock has moved up by 7.8%
- POSITIVE IMPACT
Revenue Rich
Revenue is up for the last 2 quarters, 30.01M → 37.92M (in $), with an average increase of 20.9% per quarter
NO EFFECTAgainst Peers
In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 150.9% return, outperforming this stock by 242.0%
- NO EFFECT
Against Peers
In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 62.8% return, outperforming this stock by 117.4%
NEGATIVE IMPACTProfit Down
Netprofit is down for the last 2 quarters, -23.46M → -37.25M (in $), with an average decrease of 58.8% per quarter
About Karyopharm Therapeutics Inc
| Organisation | Karyopharm Therapeutics Inc |
| Headquarters | 85 Wells Avenue, Newton, MA, United States, 02459-3298 |
| Industry | Health Technology |
| CEO | Mr. Richard A. Paulson M.B.A. |
| E-voting on shares | Click here to vote |
Key Management of Karyopharm Therapeutics Inc
Name | Title |
|---|---|
Dr. Reshma Rangwala M.D., Ph.D. | Executive VP, Chief Medical Officer & Head of Research |
Dr. Sharon Shacham M.B.A., Ph.D. | Co-Founder & Chairman of Scientific Advisory Board |
Mr. Brendan Twohig Strong | SVP of Investor Relations & Corporate Communications |
Mr. Michael J. Mano J.D. | Senior VP, General Counsel & Secretary |
Ms. Lisa DiPaolo | Executive VP & Chief Human Resource Officer |
Ms. Sohanya Cheng M.B.A. | Executive VP, Chief Commercial Officer & Head of Business Development |
Ms. Lori A. Macomber CPA | EVP, CFO & Treasurer |
Ms. Kristin Abate | VP, Chief Accounting Officer & Assistant Treasurer |
Mr. James Accumanno J.D. | Chief Compliance Officer |
Mr. Richard A. Paulson M.B.A. | President, CEO & Director |
FAQs
What is Karyopharm Therapeutics Inc share price today?
Karyopharm Therapeutics Inc share price today is $5.99 as on at the close of the market. Karyopharm Therapeutics Inc share today touched a day high of $6 and a low of $5.76.
What is the 52 week high and 52 week low for Karyopharm Therapeutics Inc share?
Karyopharm Therapeutics Inc share touched a 52 week high of $16.95 on and a 52 week low of $3.51 on . Karyopharm Therapeutics Inc stock price today i.e. is closed at $5.99,which is 64.66% down from its 52 week high and 70.66% up from its 52 week low.
What is Karyopharm Therapeutics Inc's market capitalisation today?
Karyopharm Therapeutics Inc market capitalisation is $0.00T as on .
How to invest in Karyopharm Therapeutics Inc Stock (KPTI) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Karyopharm Therapeutics Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Karyopharm Therapeutics Inc Shares that will get you 0.2504 shares as per Karyopharm Therapeutics Inc share price of $5.99 per share as on October 18, 2025 at 1:29 am IST.
What is the minimum amount required to buy Karyopharm Therapeutics Inc Stock (KPTI) from India?
Indian investors can start investing in Karyopharm Therapeutics Inc (KPTI) shares with as little as ₹87.954 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹879.54 in Karyopharm Therapeutics Inc stock (as per the Rupee-Dollar exchange rate as on ).
Based on Karyopharm Therapeutics Inc share’s latest price of $5.99 as on October 18, 2025 at 1:29 am IST, you will get 1.6694 shares of Karyopharm Therapeutics Inc. Learn more about
fractional shares .
What are the returns that Karyopharm Therapeutics Inc has given to Indian investors in the last 5 years?
Karyopharm Therapeutics Inc stock has given -97.5% share price returns and 21.02% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?