Karyopharm Therapeutics
NASDAQ: KPTI
$1.88
+0.09
(+5.03%)
as on
Karyopharm Therapeutics Stock Performance
as on September 19, 2026 at 2:16 pm IST
Day's Low
$1.67$1.88
11.17%
Downside
52 Week's Low
52 Week's High
$1.24$10.9934.04%
Downside
484.57%
Upside
Karyopharm Therapeutics share price movements today
- Previous Close
- $1.79
- Open
- $1.74
- Volume
- 2.5M
- Market Cap
- $40.6M
- Day's Low - High
- $1.67 - $1.88
- 52 Week Low - High
- $1.24 - $10.99
Karyopharm Therapeutics Historical Returns
- 1 Month Return
- -10.5 %
- 3 Month Return
- -80.16 %
- 1 Year Return
- -66.91 %
- 3 Year Return
- -89.97 %
- 5 Year Return
- -98.03 %
Karyopharm Therapeutics Stock Fundamentals & Key Indicators
Check Karyopharm Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$40.6M
EPS (TTM)
-22.32
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.00%
PE Ratio (TTM)
-0.07
Industry PE ratio
-2.37
PEG Ratio
0.00028600256189872643
EBITDA
-175.9M
Revenue (TTM)
146.6M
Profit Margin
95.88%
Return On Equity TTM
77.63%
Karyopharm Therapeutics Stock Valuation
Track how Karyopharm Therapeutics P/E has moved over time to understand its valuation trends.
Karyopharm Therapeutics in the last 5 years
Lowest (-3.89x)
December 31, 2021
Industry (-2.37x)
December 31, 2025
Today (-0.41x)
December 31, 2025
Highest (-0.41x)
December 31, 2025
Today’s Price to Earnings Ratio: -0.41x
Karyopharm Therapeutics vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Karyopharm Therapeutics with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % | Dividend Yield % |
|---|---|---|---|---|---|---|
| BUY | $40.6M | -98.03% | -0.07 | 95.88% | 0.00% | |
| BUY | $63.1B | -63.24% | -19.81 | -12.57% | 0.00% | |
| BUY | $130.1B | 174.21% | 29.81 | 86.04% | 0.00% | |
| BUY | $79.7B | 21.1% | 18.48 | 84.86% | 0.48% |
Stock Returns calculator for Karyopharm Therapeutics Stock including INR - Dollar returns
The Karyopharm Therapeutics stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.
Investment Value
₹1,00,000
Karyopharm Therapeutics investment value today
Current value as on today
₹37,819
Returns
Returns from Karyopharm Therapeutics Stock
Dollar Impact
₹3,069 (+3.07%)
Analyst Recommendation on Karyopharm Therapeutics Stock
Based on 6 analysts
66.67%
Buy
33.33%
Hold
0.00%
Sell
Based on 6 analysts, 66.66666666666666% of analysts recommend a 'BUY' rating for Karyopharm Therapeutics. Average target price of $7.25
Karyopharm Therapeutics Share Price Target
Get share price movements and forecasts by analysts on Karyopharm Therapeutics.
What analysts predicted
74.07%UPSIDE
Target Price
$7.25
Current Price
$1.88
Analyzed by
6 Analysts
Target
$7.25
Karyopharm Therapeutics target price $7.25, a slight upside of 74.07% compared to current price of $1.88. According to 6 analysts rating.
Indian Investors' Interest in Karyopharm Therapeutics Stock
Search interest for Karyopharm Therapeutics Stock has increased by 3% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:3% versus previous 30 day period
Karyopharm Therapeutics Quarterly Profit & Loss
All numbers in Millions USD
Karyopharm Therapeutics Annual Profit & Loss
All numbers in Millions USD
Karyopharm Therapeutics Quarterly Cash Flow
All numbers in Millions USD
Karyopharm Therapeutics Annual Cash Flow
All numbers in Millions USD
Karyopharm Therapeutics News & Key Events
Today's Timeline - 11 September
Fri, 05:25 PM
-Karyopharm enters forbearance agreement, delaying $15.8M debt payment and allowing time for negotiations and strategic alternatives.
Insights on Karyopharm Therapeutics
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise
In the last 7 days, KPTI stock has moved up by 16.8%
NO EFFECTAgainst Peers
In the last 3 years, Moderna, Inc. Common Stock has given 48.8% return, outperforming this stock by 138.3%
- NO EFFECT
Against Peers
In the last 1 year, Moderna, Inc. Common Stock has given 510.3% return, outperforming this stock by 575.5%
NEGATIVE IMPACTProfit Down
Netprofit is down for the last 2 quarters, -22.39M → -67.02M (in $), with an average decrease of 199.3% per quarter
- NEGATIVE IMPACT
Revenue Fall
Revenue is down for the last 2 quarters, 35.06M → 33.43M (in $), with an average decrease of 4.7% per quarter
About Karyopharm Therapeutics
| Organisation | Karyopharm Therapeutics |
| Headquarters | 85 Wells Avenue, Newton, MA, 02459-3298, US |
| Industry | Biotechnology |
| CEO | Richard A. Paulson |
| E-voting on shares | Click here to vote |
Key Management of Karyopharm Therapeutics
Name | Title |
|---|---|
Dr. Reshma Rangwala M.D., Ph.D. | Executive VP, Chief Medical Officer & Head of Research |
Dr. Sharon Shacham M.B.A., Ph.D. | Co-Founder & Chairman of Scientific Advisory Board |
Mr. Brendan Twohig Strong | Senior Vice President of Investor Relations |
Mr. James Accumanno J.D. | Chief Compliance Officer |
Ms. Lisa DiPaolo | Executive VP & Chief Human Resource Officer |
Mr. Richard A. Paulson M.B.A. | President, CEO & Director |
Mr. Stuart Poulton | Executive VP & Chief Development Officer |
Ms. Lori A. Macomber CPA | EVP, CFO & Treasurer |
Ms. Kristin Abate | VP, Chief Accounting Officer & Assistant Treasurer |
Mr. Michael J. Mano J.D. | Executive VP, Chief Legal Officer & Secretary |
FAQs
What is Karyopharm Therapeutics share price today?
Karyopharm Therapeutics share price today is $1.88 as on at the close of the market. Karyopharm Therapeutics share today touched a day high of $1.88 and a low of $1.67.
What is the 52 week high and 52 week low for Karyopharm Therapeutics share?
Karyopharm Therapeutics share touched a 52 week high of $10.99 on and a 52 week low of $1.24 on . Karyopharm Therapeutics stock price today i.e. is closed at $1.88,which is 82.89% down from its 52 week high and 51.61% up from its 52 week low.
What is Karyopharm Therapeutics's market capitalisation today?
Karyopharm Therapeutics market capitalisation is $0.00T as on .
How to invest in Karyopharm Therapeutics Stock (KPTI) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Karyopharm Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Karyopharm Therapeutics Shares that will get you 0.7979 shares as per Karyopharm Therapeutics share price of $1.88 per share as on September 19, 2026 at 8:46 am IST.
What is the minimum amount required to buy Karyopharm Therapeutics Stock (KPTI) from India?
Indian investors can start investing in Karyopharm Therapeutics (KPTI) shares with as little as ₹95.88 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹958.80 in Karyopharm Therapeutics stock (as per the Rupee-Dollar exchange rate as on ).
Based on Karyopharm Therapeutics share’s latest price of $1.88 as on September 19, 2026 at 8:46 am IST, you will get 5.3191 shares of Karyopharm Therapeutics. Learn more about
fractional shares .
What are the returns that Karyopharm Therapeutics has given to Indian investors in the last 5 years?
Karyopharm Therapeutics stock has given -98.03% share price returns and 30.29% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?