SPRUCE BIOSCIENCES INC Share Price

NASDAQ: SPRB

Small Cap

$9.02

-0.56

(-5.85%)

as on September 18, 2025 at 1:29 am IST

$₹

SPRUCE BIOSCIENCES INC Stock Performance

as on September 18, 2025 at 1:29 am IST

Day's Low
Day's High
$8.87
Day's Price Range
$10.1
$9.02
1.66%
Downside
11.97%
Upside
52 Week's Low
52 Week's High
$0.08
52-Week Price Range
$12.75
$9.02
99.14%
Downside
41.35%
Upside

SPRUCE BIOSCIENCES INC share price movements today

Previous Close: $9.58
Open: $9.50
Volume: 107.3K
Day's Low - High: $8.87 - $10.1
52 Week Low - High: $0.08 - $12.75

SPRUCE BIOSCIENCES INC Historical Returns

1 Month Return: 0 %
3 Month Return: + 75.7 %
1 Year Return: + 2021.82 %
3 Year Return: + 463.53 %
5 Year Return: 0 %

SPRUCE BIOSCIENCES INC Stock Fundamentals & Key Indicators

Check SPRUCE BIOSCIENCES INC market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$5.4M

EPS (TTM)

-2.83

Dividend Yield

0.00%

PE Ratio (TTM)

P/B Ratio

PEG Ratio

Return On Equity TTM

20599400.00%

SPRUCE BIOSCIENCES INC vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of SPRUCE BIOSCIENCES INC with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %
SPRUCE BIOSCIENCES INC	BUY	$5.4M	NA	NA	0.00%
Alnylam Pharmaceuticals, Inc.	BUY	$60.5B	252.04%	-505.15	-12.96%
Beone Medicines Ltd	NA	$39.0B	NA	NA	-3.89%
Vertex Pharmaceuticals Incorporated	BUY	$100.3B	44.17%	27.85	31.86%
Regeneron Pharmaceuticals, Inc.	BUY	$59.6B	1.78%	14.1	31.37%

Stock Returns calculator for SPRUCE BIOSCIENCES INC Stock including INR - Dollar returns

The SPRUCE BIOSCIENCES INC stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

SPRUCE BIOSCIENCES INC investment value today

Current value as on today

₹20,09,043

Returns

₹19,09,043

(+1.91K%)

Returns from SPRUCE BIOSCIENCES INC Stock

₹19,04,444 (+1.9K%)

Dollar Returns*

₹4,598 (+4.6%)

Analyst Recommendation on SPRUCE BIOSCIENCES INC Stock

Based on 13 analysts

BUY

53.85%

Buy

46.15%

Hold

0.00%

Sell

Based on 13 analysts, 53.85% of analysts recommend a 'BUY' rating for SPRUCE BIOSCIENCES INC. Average target price of $10

SPRUCE BIOSCIENCES INC Share Price Target

Get share price movements and forecasts by analysts on SPRUCE BIOSCIENCES INC.

What analysts predicted

9.8%UPSIDE

Target Price

$10

Current Price

$9.02

Analyzed by

13 Analysts

Target

$10.00

SPRUCE BIOSCIENCES INC target price $10, a slight upside of 9.8% compared to current price of $9.02. According to 13 analysts rating.

SPRUCE BIOSCIENCES INC Quarterly Profit & Loss

All numbers in Millions USD

	Mar 2023	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Total Revenue	1	2	3	2	2	1	0	0	0	-
Gross Profit	1	2	3	2	2	1	0	-	0	-
Operating Income	-13	-13	-13	-11	-12	-10	-9	-24	-14	-2
EBITDA	-12	-12	-12	-9	-11	-9	-8	-	-13	-2
Interest Expense	0	0	0	0	0	0	0	0	0	0
Depreciation	0	0	0	0	0	0	0	0	0	0
Income Before Tax	-12	-12	-12	-9	-11	-9	-8	-23	-14	-2
Income Tax Expense	0	1	0	0	0	-	-	-	-	-
Net Income	-12	-12	-12	-9	-11	-9	-8	-23	-14	-2
Net Profit Margin	-651.27%	-592.33%	-402.02%	-344.65%	-580.67%	-570.25%	-1440.37%	-3380.06%	-2014.49%	0.00%

SPRUCE BIOSCIENCES INC Annual Profit & Loss

All numbers in Millions USD

	Dec 2018	Dec 2019	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Total Revenue	-	-	-	-	1	10	4
Gross Profit	0	0	0	0	0	10	4
Operating Income	-9	-13	-29	-42	-47	-51	-56
EBITDA	-9	-13	-29	-41	-45	-47	-52
Interest Expense	-	0	0	0	0	0	0
Depreciation	0	0	0	0	0	0	0
Income Before Tax	-9	-13	-29	-42	-46	-47	-53
Income Tax Expense	0	0	0	0	-1	0	-
Net Income	-9	-13	-30	-42	-46	-47	-53
Net Profit Margin	0.00%	0.00%	0.00%	0.00%	-2351.32%	-474.96%	-1079.94%

SPRUCE BIOSCIENCES INC Quarterly Cash Flow

All numbers in Millions USD

	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Net Income	-12	-12	-9	-11	-9	-8	-23	-14	-2
Operating Cash Flow	1	-12	-11	-14	-11	-9	-20	-12	-8
Investing Cash Flow	22	13	9	-	-	-	-	-	-
Financing Cash Flow	0	0	0	0	0	0	0	0	0
Change in Cash	23	1	-2	-15	-11	-9	-21	-13	-9

SPRUCE BIOSCIENCES INC Annual Cash Flow

All numbers in Millions USD

	Dec 2019	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Net Income	-13	-29	-42	-46	-47	-53
Operating Cash Flow	-12	-27	-35	-41	-33	-55
Investing Cash Flow	0	0	-79	23	55	-
Financing Cash Flow	12	181	0	0	49	-1
Change in Cash	0	153	-114	-18	71	-57

Global Institutional Holdings in SPRUCE BIOSCIENCES INC

Funds	Holdings
RiverVest Venture Management LLC	6.96%
The Carlyle Group Inc	6.86%
Rock Springs Capital Management LP	6.18%
Ikarian Capital, LLC	2.37%
Vanguard Group Inc	2%

See all

Insights on SPRUCE BIOSCIENCES INC

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

POSITIVE IMPACT
Price Rise
In the last 6 months, SPRB stock has moved up by 2799.5%
POSITIVE IMPACT
Best in 1 Year
In the last 1 year, SPRB has outperformed top 5 stocks with highest market-cap in its industry
POSITIVE IMPACT
Best in 3 Years
In the last 3 years, SPRB has outperformed top 5 stocks with highest market-cap in its industry

About SPRUCE BIOSCIENCES INC

spruce biosciences is a clinical stage biopharmaceutical company focused on developing novel therapies for rare diseases affecting the endocrine system.

Organisation	SPRUCE BIOSCIENCES INC
Headquarters	611 Gateway Boulevard, South San Francisco, CA, United States, 94080
Industry	Commercial Services
CEO	Dr. Javier Szwarcberg M.D., M.P.H.
E-voting on shares	Click here to vote

Key Management of SPRUCE BIOSCIENCES INC

Name	Title
Dr. Javier Szwarcberg M.D., M.P.H.	CEO & Director
Mr. Samir M. Gharib CPA, M.B.A.	President & CFO
Dr. Kirk Ways M.D., Ph.D.	Chief Medical Officer & Director
Mr. Michael G. Grey	Executive Chairman

FAQs

What is SPRUCE BIOSCIENCES INC share price today?

SPRUCE BIOSCIENCES INC share price today is $9.02 as on September 18, 2025 at 1:29 am IST at the close of the market. SPRUCE BIOSCIENCES INC share today touched a day high of $10.1 and a low of $8.87.

What is the 52 week high and 52 week low for SPRUCE BIOSCIENCES INC share?

SPRUCE BIOSCIENCES INC share touched a 52 week high of $12.75 on September 12, 2025 and a 52 week low of $0.08 on April 28, 2025. SPRUCE BIOSCIENCES INC stock price today i.e. September 18, 2025 at 1:29 am IST is closed at $9.02,which is 29.25% down from its 52 week high and 11478.95% up from its 52 week low.

What is SPRUCE BIOSCIENCES INC's market capitalisation today?

SPRUCE BIOSCIENCES INC market capitalisation is $0.00T as on September 18, 2025 at 1:29 am IST.

How to invest in SPRUCE BIOSCIENCES INC Stock (SPRB) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for SPRUCE BIOSCIENCES INC on INDmoney app. Click on Buy button. You can invest as low as $1.5 in SPRUCE BIOSCIENCES INC Shares that will get you 0.1663 shares as per SPRUCE BIOSCIENCES INC share price of $9.02 per share as on September 18, 2025 at 1:29 am IST.

What is the minimum amount required to buy SPRUCE BIOSCIENCES INC Stock (SPRB) from India?

Indian investors can start investing in SPRUCE BIOSCIENCES INC (SPRB) shares with as little as ₹87.816 or $1 (as of September 18, 2025 at 2:40 am IST) using the INDmoney app.
For example: If you want to invest $10 or ₹878.16 in SPRUCE BIOSCIENCES INC stock (as per the Rupee-Dollar exchange rate as on September 18, 2025 at 2:40 am IST). Based on SPRUCE BIOSCIENCES INC share’s latest price of $9.02 as on September 18, 2025 at 1:29 am IST, you will get 1.1086 shares of SPRUCE BIOSCIENCES INC. Learn more about fractional shares .