Spruce Biosciences, Inc. Common Stock share price logo

Spruce Biosciences, Inc. Common Stock

NASDAQ: SPRB

Small Cap

$56.95

-0.92

(-1.59%)

as on

Spruce Biosciences, Inc. Common Stock Stock Performance

as on May 8, 2026 at 6:57 am IST

  • Day's Low

    Day's High

    $55.55
    $57.39
    downward going graph

    2.46%

    Downside

    0.77%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $4.35
    $240.00
    downward going graph

    92.36%

    Downside

    321.42%

    Upside

    downward going graph

Spruce Biosciences, Inc. Common Stock share price movements today

Previous Close
$57.87
Open
$57.08
Volume
125.0K
Day's Low - High
$55.55 - $57.39
52 Week Low - High
$4.35 - $240.00

Spruce Biosciences, Inc. Common Stock Historical Returns

1 Month Return
-6.89 %
3 Month Return
-20.07 %
1 Year Return
0 %
3 Year Return
+ 2416.09 %
5 Year Return
+ 275.54 %

Spruce Biosciences, Inc. Common Stock Stock Fundamentals & Key Indicators

Check Spruce Biosciences, Inc. Common Stock market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$160.4M

EPS (TTM)

-24.5325

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

EBITDA

-28.6M

Revenue (TTM)

697.0K

Profit Margin

0.00%

Return On Equity TTM

-109.25%

Spruce Biosciences, Inc. Common Stock vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Spruce Biosciences, Inc. Common Stock with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
BUY$160.4M275.54%NA0.00%
BUY$40.5B130.77%76.3212.55%
NA$32.5BNA70.895.37%
BUY$108.5B98.9%25.3835.51%
BUY$75.6B45.15%17.629.65%

Stock Returns calculator for Spruce Biosciences, Inc. Common Stock Stock including INR - Dollar returns

The Spruce Biosciences, Inc. Common Stock stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 3Y

  • 5Y

Spruce Biosciences, Inc. Common Stock investment value today

Current value as on today

₹28,53,344

Returns

₹27,53,344

(+2.75K%)

Returns from Spruce Biosciences, Inc. Common Stock Stock

₹23,76,087 (+2.38K%)

Dollar Impact

₹3,77,257 (+377.26%)

Analyst Recommendation on Spruce Biosciences, Inc. Common Stock Stock

Based on 13 analysts

BUY

53.85%

Buy

46.15%

Hold

0.00%

Sell

Based on 13 analysts, 53.85% of analysts recommend a 'BUY' rating for Spruce Biosciences, Inc. Common Stock. Average target price of $186.6

Spruce Biosciences, Inc. Common Stock Share Price Target

Get share price movements and forecasts by analysts on Spruce Biosciences, Inc. Common Stock.

What analysts predicted

69.48%UPSIDE

Target Price

$186.6

Current Price

$56.95

Analyzed by

13 Analysts

Target

$186.60

Spruce Biosciences, Inc. Common Stock target price $186.6, a slight upside of 69.48% compared to current price of $56.95. According to 13 analysts rating.

Indian Investors' Interest in Spruce Biosciences, Inc. Common Stock Stock

Search interest for Spruce Biosciences, Inc. Common Stock Stock has increased by 59% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:59% versus previous 30 day period

Spruce Biosciences, Inc. Common Stock Quarterly Profit & Loss

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Total Revenue
3
2
2
1
0
0
0
-
-
-
Gross Profit
3
2
2
1
0
-
0
-
-
0
Operating Income
-13
-11
-12
-10
-9
-24
-14
-2
-8
-11
EBITDA
-12
-9
-11
-9
-8
-
-13
-2
-8
-11
Interest Expense
0
0
0
0
0
0
0
0
0
0
Depreciation
0
0
0
0
0
0
0
0
0
0
Income Before Tax
-12
-9
-11
-9
-8
-23
-14
-2
-8
-14
Income Tax Expense
0
0
0
-
-
-
-
-
-
-
Net Income
-12
-9
-11
-9
-8
-23
-14
-2
-8
-14
Net Profit Margin
-402.02%
-344.65%
-580.67%
-570.25%
-1440.37%
-3380.06%
-2014.49%
0.00%
0.00%
0.00%

Spruce Biosciences, Inc. Common Stock Annual Profit & Loss

All numbers in Millions USD

Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
-
-
-
-
1
10
4
-
Gross Profit
0
0
0
0
0
10
4
0
Operating Income
-9
-13
-29
-42
-47
-51
-56
-36
EBITDA
-9
-13
-29
-41
-45
-47
-52
-36
Interest Expense
-
0
0
0
0
0
0
0
Depreciation
0
0
0
0
0
0
0
0
Income Before Tax
-9
-13
-29
-42
-46
-47
-53
-38
Income Tax Expense
0
0
0
0
-1
0
-
-
Net Income
-9
-13
-29
-42
-46
-47
-53
-38
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
-2351.32%
-474.96%
-1079.94%
0.00%

Spruce Biosciences, Inc. Common Stock Quarterly Cash Flow

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Net Income
-9
-11
-9
-8
-23
-14
-2
-8
-14
Operating Cash Flow
-11
-14
-11
-9
-20
-12
-8
-5
-6
Investing Cash Flow
9
-
-
-
-
-
-
-
-
Financing Cash Flow
0
0
0
0
0
0
0
0
44
Change in Cash
-2
-15
-11
-9
-21
-13
-9
-5
38

Spruce Biosciences, Inc. Common Stock Annual Cash Flow

All numbers in Millions USD

Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-13
-29
-42
-46
-47
-53
-38
Operating Cash Flow
-12
-27
-35
-41
-33
-55
-33
Investing Cash Flow
0
0
-79
23
55
-
-
Financing Cash Flow
12
181
0
0
49
-1
43
Change in Cash
0
153
-114
-18
71
-57
10

Global Institutional Holdings in Spruce Biosciences, Inc. Common Stock

Funds
Holdings
Northern Trust Corp
0.19%
Caligan Partners LP
0.76%
Stonepine Capital Management Llc
0.73%
Ikarian Capital, LLC
4.49%
SkyView Investment Advisors, LLC
0.22%

Spruce Biosciences, Inc. Common Stock News & Key Events

  • img

    Today's Timeline - 08 October

    Thu, 02:02 AM

    -

    Spruce Biosciences announces $50M private placement to advance enzyme replacement therapy for Sanfilippo Syndrome Type B.

Insights on Spruce Biosciences, Inc. Common Stock

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 year, SPRB stock has moved up by 73526.0%

  • imgPOSITIVE IMPACT

    Best in 3 Years

    img

    In the last 3 years, SPRB has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Best in 1 Year

    img

    In the last 1 year, SPRB has outperformed top 5 stocks with highest market-cap in its industry

About Spruce Biosciences, Inc. Common Stock

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.
OrganisationSpruce Biosciences, Inc. Common Stock
Headquarters611 Gateway Boulevard, South San Francisco, CA, United States, 94080
IndustryBiotechnology
CEODr. Javier Szwarcberg M.D., M.P.H.
E-voting on sharesClick here to vote

Key Management of Spruce Biosciences, Inc. Common Stock

Name

Title

Dr. Javier Szwarcberg M.D., M.P.H.

CEO & Director

Mr. Samir M. Gharib CPA, M.B.A.

President & CFO

Dr. Kirk Ways M.D., Ph.D.

Chief Medical Officer & Director

Mr. Bruno Gagnon BPHARM, M.Sc.

Senior Vice President of Clinical Development Operations

Dr. Daven Mody Pharm.D.

Senior Vice President of Regulatory & Quality

Mr. Corwin Dale Hooks

Chief Commercial Officer

Mr. Michael G. Grey

Executive Chairman

FAQs

What is Spruce Biosciences, Inc. Common Stock share price today?

Spruce Biosciences, Inc. Common Stock share price today is $56.95 as on at the close of the market. Spruce Biosciences, Inc. Common Stock share today touched a day high of $57.39 and a low of $55.55.

What is the 52 week high and 52 week low for Spruce Biosciences, Inc. Common Stock share?

Spruce Biosciences, Inc. Common Stock share touched a 52 week high of $240 on and a 52 week low of $4.35 on . Spruce Biosciences, Inc. Common Stock stock price today i.e. is closed at $56.95,which is 76.27% down from its 52 week high and 1209.20% up from its 52 week low.

What is Spruce Biosciences, Inc. Common Stock's market capitalisation today?

Spruce Biosciences, Inc. Common Stock market capitalisation is $0.00T as on .

How to invest in Spruce Biosciences, Inc. Common Stock Stock (SPRB) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Spruce Biosciences, Inc. Common Stock on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spruce Biosciences, Inc. Common Stock Shares that will get you 0.0263 shares as per Spruce Biosciences, Inc. Common Stock share price of $56.95 per share as on May 8, 2026 at 1:27 am IST.

What is the minimum amount required to buy Spruce Biosciences, Inc. Common Stock Stock (SPRB) from India?

Indian investors can start investing in Spruce Biosciences, Inc. Common Stock (SPRB) shares with as little as ₹94.24 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹942.40 in Spruce Biosciences, Inc. Common Stock stock (as per the Rupee-Dollar exchange rate as on ). Based on Spruce Biosciences, Inc. Common Stock share’s latest price of $56.95 as on May 8, 2026 at 1:27 am IST, you will get 0.1756 shares of Spruce Biosciences, Inc. Common Stock. Learn more about fractional shares .

What are the returns that Spruce Biosciences, Inc. Common Stock has given to Indian investors in the last 5 years?

Spruce Biosciences, Inc. Common Stock stock has given 275.54% share price returns and 29.81% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?